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Preclinical In Vivo Research in
Mispro Facilities

Purpose-built for next-generation therapeutics

Mispro offers research-ready environments for preclinical in vivo research, supporting non-GLP studies across modalities and indications to help teams generate reproducible, decision-grade data.

Tell Us About Your Research

In Vivo Pharmacology & Translational Research

Mispro's research environments support early-stage non-GLP pharmacology, efficacy, and safety assessment studies in murine (mice) and rat models within controlled BSL-1 and BSL-2 environments. Stable environmental parameters and integrated veterinary oversight strengthen reproducibility and downstream data interpretation.

Common research applications include:

  • In Vivo Pharmacology
  • Target validation and mechanism-of-action studies
  • PK and PD assessments
  • Dose-ranging and tolerability studies
  • Oncology efficacy models
  • Immunology and inflammatory disease models
  • Neurobiology and CNS research
  • Infectious Disease
  • Rare Disease Modeling
  • Combination therapy evaluation
"Rodents are the most commonly used animal models in biomedical research today, representing over 95% of all animals studied. Because of the conservation of biological principles & processes (anatomy, physiology, etc.) across mammalian species, we can study cellular pathways & disease in the mouse or rat model and use that information to develop potential targets, novel approaches, and therapies for unmet medical need in the human condition." — Keith Astrofsky, Corporate Veterinarian & Scientific Advisor, Mispro

Therapeutic Modalities & Drug Delivery

Mispro supports advanced and emerging therapeutic modalities within biosecure, environmentally controlled, AAALAC-accredited vivarium environments aligned with pharmaceutical diligence expectations.

These conditions support scientific integrity across complex and evolving platforms, including:

  • Cell Therapies
  • CAR T and engineered immune cell therapies
  • Stem Cell and iPSC-derived therapies
  • Gene Therapies and viral vector platforms
  • Gene Editing, including CRISPR-based approaches
  • Oncolytic viruses
  • Bacteriophage and live biotherapeutic products
  • Protein and antibody therapeutics
  • Nanoparticle and synthetic vesicle platforms
  • Advanced small and large molecule delivery systems

Additional Fields of Research

In addition to core translational programs, Mispro environments support a wide spectrum of therapeutic disciplines and organ-system–based research, enabling rigorous in vivo investigation across diverse disease biology, including:

  • Gastroenterology & Metabolic Disease
  • Cardiovascular Medicine
  • Hematology & Nephrology
  • Pulmonology
  • Hepatology
  • Ophthalmology

High-Impact Areas

Explore how Mispro’s AAALAC-accredited environments are specifically designed to support complex in vivo research across high-impact therapeutic areas, with infrastructure, services and oversight specifically designed to sustain reproducibility and translational rigor.


Innovation Across Our Network

  • 88% Novel / Proprietary Research
  • 58% Translational Programs
  • 46% Platform Companies
  • 75% Of biotech M&A activity in 2025

FAQs

  • What animal models are available for in vivo research at Mispro?

    Mispro contract vivarium facilities support in vivo research with mouse and rat models of varying strains and health status.

  • Does Mispro support non-GLP preclinical studies?

    Yes. Mispro provides research-ready environments for BSL-1 and BSL-2 non-GLP in vivo pharmacology, efficacy, PK/PD, tolerability, behavioral, and other preclinical studies.

  • Does Mispro provide veterinary and animal husbandry support?

    Yes. Mispro provides certified animal husbandry, veterinary oversight, and technical support to help researchers maintain consistent, ethical and humane in vivo studies.

  • Are Mispro facilities AAALAC-accredited?

    Yes. Mispro facilities are AAALAC-accredited, ensuring the industry's gold standard for laboratory animal research environments, inclusive of animal care and welfare, facility management, and regulatory compliance.

  • What regulatory oversight is provided for studies conducted at Mispro?

    Mispro is AAALAC-accredited and provides regulatory oversight and compliance support, including IACUC approval, OLAW/PHS assurance, and veterinary oversight. All preclinical research in Mispro facilities requires in-house IACUC approval.

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